Father Fred McDonough rode his bicycle around the neighborhood in 1912 to organize Park Hill Catholics. He gained a new parish, which initially met for Mass in the original Park Hill Methodist Episcopal Church at 23rd and Dexter.

This fledgling parish built a Neoclassical, gray brick, three-story chapel rectory-parish hall, adorned with Corinthian pilasters, in 1913. It is now the elementary school. During the prosperous 1920s, the growing parish commissioned Denver architect Harry James Manning to design a $250,000 Gothic church with twin spires soaring over Montview Boulevard. The Great Depression killed this cathedral-sized fantasy. Manning died in 1933 and his associate, William F. Andres, scaled back the project considerably. The present one-story church opened in 1935.

Blessed Sacrament remains an interesting example of Gothic Revival with its abbreviated front towers, square-cut, ashlar limestone walls, rich but miniature Gothic stained-glass windows, slit windows, and mini-buttresses. Further additions included a parish school, the 1923 rectory at 4930 Montview just east of the church, and a 1942 convent (now a Park Hill residence) at 1901 Eudora to house the ten sisters teaching grade school. The $225,000 Machebeuf Junior High School [1973 Elm St.] was completed in 1951 and named for Denver’s pioneer missionary priest and the first bishop of Colorado, Joseph Projectus Machebeuf. Another $250,000 later in 1958, Machebeuf High School opened. After the high school moved to the Lowry neighborhood in 2000, its former building became part of the Blessed Sacrament Preschool and Middle School.